Science of Nanoscale Systems and their Device Applications
Science of Nanoscale Systems and their Device Applications
2006 Research Results

Nanomaterials Guiding Antimicrobial Host Defense
J. Mizgerd (Harvard School of Public Health)

 

 

Polymers of polyacrylamide, ~100 nm in size, were engineered to coat gram-positive bacteria with antibodies in order to stimulate phagocytosis by macrophages. Polymers present vancomycin (for attaching to bacteria) and fluorescin (for attaching anti-fluorescin antibodies). Bacteria coated with antibodies can be visualized inside of macrophages, (a) using stains or (b) using the fluorescent nature of the polymers coating the bacteria.

 

 

  Last Modified June 20, 2006 by the NSEC Office.